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王陵军

发布时间:2020-07-13  点击:[]


 王陵军,医学博士、博士后,教授,博士研究生导师、博士后合作导师,岭南医学研究中心负责人。中华中医药学会中青年创新人才,广东省杰出青年医学人才,广州中医药大学第一附属医院“首届杰出中青年医学人才”,广东省“千百十人才”工程培养对象,广州中医药大学“青年英才培养工程”培养对象,国家自然科学基金项目评审专家,现任中华中医药学会内科分会会常务委员、中华中医药学会心血管病分会常务委员,世界中医药学会联合会内科专业委员会理事、世界中医药学会联合会痰证学专业委员会常务理事、广东省中医药学会内科专业委员会常务委员、广东省自然医学会干细胞与中医再生医学专业委员会副主任委员。曾公派至美国密歇根大学安娜堡分校心血管中心留学2年。现主要从事心血管疾病中医药防治的科研、临床、教学工作。主持国家自然科学基金4项,广东省自然科学基金重点项目1项,广东省自然科学基金博士启动项目1项,中国博士后基金1项,广州市慢性心力衰竭中医药防治重点实验室骨干成员。在《Cardiovascular Research》、《British Journal of Pharmacology》、《Acta Diabetologica》、《AJP - Heart and Circulatory》、《Stem Cell Research & Therapy》、《Cell Death & Disease》、《Pharmacological Research》等学术期刊发表学术论文40多篇。培养和协助培养博士研究生10名、硕士研究生14名。

代表性文章:

[1]Ni SH#, Xu JD#, Sun SN, Li Y, Zhou Z, Li H, Liu X, Deng JP, Huang YS, Chen ZX, Feng WJ, Wang JJ, Xian SX, Yang ZQ*, Wang S*, Wang LJ*, Lu L*. Single-cell transcriptomic analyses of cardiac immune cells reveal that Rel-driven CD72-positive macrophages induce cardiomyocyte injury. Cardiovasc Res. 2022 Mar 25;118(5):1303-1320.(IF:13.08中科院分区:Q1)

[2]Zhang L, He J, Wang J, Liu J, Chen Z, Deng B, Wei L, Wu H, Liang B, Li H, Huang Y, Lu L, Yang Z, Xian S, Wang L*. Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy. Cell Death Dis. 2021 May 11;12(5):470.(IF:9.685JCR分区:Q1)

[3] Wang J, Deng B, Liu Q, Huang Y, Chen W, Li J, Zhou Z, Zhang L, Liang B, He J, Chen Z, Yan C, Yang Z, Xian S, Wang L*. Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload. Cell Death Dis. 2020 Jul 24;11(7):574.(IF:9.685JCR分区:Q1)

[4] Sun SN#, Ni SH#, Li Y#, Liu X, Deng JP, Chen ZX, Li H, Feng WJ, Huang YS, Li DN, Xian SX, Yang ZQ*, Wang LJ*, Lu L*. G-MDSCs promote aging-related cardiac fibrosis by activating myofibroblasts and preventing senescence. Cell Death Dis. 2021 Jun 8;12(6):594.(IF:9.685JCR分区:Q1)

[5] Guan Z, Chen J, Wang L, Hao M, Dong X, Luo T, Jiang J, Lin Z, Li X, Chen P, Yang Z, Ye X*, Wang L*, Xian S*, Chen Z*. Nuanxinkang prevents the development of myocardial infarction-induced chronic heart failure by promoting PINK1/Parkin-mediated mitophagy. Phytomedicine. 2023 Jan;108:154494.(IF:6.658,JCR分区:Q1)

[6] Ni SH, OuYang XL, Liu X, Lin JH, Li Y, Sun SN, Deng JP, Han XW, Zhang XJ, Li H, Huang YS, Chen ZX, Lian ZM, Wang ZK, Long WJ*, Wang LJ*, Yang ZQ*, Lu L*. A molecular phenotypic screen reveals that lobetyolin alleviates cardiac dysfunction in 5/6 nephrectomized mice by inhibiting osteopontin. Phytomedicine. 2022 Dec;107:154412.(IF:6.658,JCR分区:Q1)

[7] Zhang L, Guo YN, Liu J, Wang LH, Wu HQ, Wang T, Deng B, Wang JY, Lu L, Chen ZX, He JQ, Liang BR, Li H, Huang YS, Yang ZQ, Xian SX, Wang LJ*, Ye XH*. Plantamajoside attenuates cardiac fibrosis via inhibiting AGEs activated-RAGE/autophagy/EndMT pathway. Phytother Res. 2023 Mar;37(3):834-847.(IF:6.388,JCR分区:Q1)

[8] Ni SH, Sun SN, Zhou Z, Li Y, Huang YS, Li H, Wang JJ, Xiao W, Xian SX, Yang ZQ, Wang LJ*, Lu L*. Arctigenin alleviates myocardial infarction injury through inhibition of the NFAT5-related inflammatory phenotype of cardiac macrophages/monocytes in mice. Lab Invest. 2020 Apr;100(4):527-541. (IF:5.502,JCR分区:Q1)

[9]Tao YG, Huang XF, Wang JY, Kang MR, Wang LJ*, Xian SX*. Exploring Molecular Mechanism of Huangqi in Treating Heart Failure Using Network Pharmacology. Evid Based Complement Alternat Med. 2020 Apr 23;2020:6473745.( IF:2.650; JCR分区:Q3.)

[10] Huang ZY#, Wang LJ#,Wang JJ#, Feng WJ, Yang ZQ, Ni SH, Huang YS, Li H, Yang Y, Wang MQ, Hu R, Wan H, Wen CJ, Xian SX*, Lu L*. Hispaglabridin B, a liquorice extract discovered by a bioinformatics and machine learning approach, relieves protein-energy wasting by inhibiting FoxO1. Br J Pharmacol. 2019 Jan;176(2):267-281.(IF:9.319; JCR分区:Q1.)

[11] Chen Z#, Luo T, Zhang L, Zhou Z, Huang Y, Lu L, Yang Z, Wang L*, Xian S*. A simplified herbal formula for the treatment of heart failure: Efficacy, bioactive ingredients, and mechanisms. Pharmacol Res. 2019 Sep;147:104251.(IF:10.334JCR分区:Q1

[12] Ni SH#, Sun SN, Huang ZY, Huang YS, Li H, Wang JJ, Xian SX, Yang ZQ, Wang LJ*,Lu L*. The pleiotropic association between IL-10 levels and CVD prognosis:Evidence from a meta-analysis. Cytokine. 2019 Mar 12;119:37-46.( IF:3.861,JCR分区:Q1.)

[13] Liang B, Yan C, Zhang L, Yang Z, Wang L*, Xian S*, Lu L*. The Effect of Acupuncture and Moxibustion on Heart Function in Heart Failure Patients: A Systematic Review and Meta-Analysis. Evidence-based complementary and alternative medicine : eCAM 2019;2019: 6074967. IF:4.77;JCRQ2

[14] Huang YF#, Niu WB#, Hu R#, Wang LJ#, Huang ZY#, Ni SH, Wang MQ, Yang Y, Huang YS, Feng WJ, Xiao W*, Zhu DJ*, Xian SX*, Lu L*. FIBP knockdown attenuates growth and enhances chemotherapy in colorectal cancer via regulating GSK3β-related pathways. Oncogenesis. 2018 Oct 2;7(9):77.( IF:7.485; JCR分区:Q1.)

[15] Gao W, Zhou Z, Liang B, Huang YS, Yang ZQ, Chen Y, Zhang L, Yan C, Wang J, Lu L, Wen Z, Xian SX*, Wang LJ *. Inhibiting Receptor of Advanced Glycation End Products Attenuates Pressure Overload-Induced Cardiac Dysfunction by Preventing Excessive Autophagy. Front Physiol. 2018 Sep 24;9:1333.( IF:4.134; JCR分区:Q2.)

[16] Wang LJ#, Meier EM, Tian S, Lei I, Liu L, Xian SX, Lam MT, Wang Z*.Transplantation of Isl1(+) cardiac progenitor cells in small intestinal submucosa improves infarcted heart function. Stem Cell Res Ther. 2017 Oct 16;8(1):230. (IF:5.985; JCR分区:Q1.)

[17] Wang LJ#, Wang MQ, Hu R, Yang Y, Huang YS, Xian SX*, Lu L*. Effect of Zinc Supplementation on Maintenance Hemodialysis Patients: A Systematic Review and Meta-Analysis of 15 Randomized Controlled Trials. Biomed Res Int.2017:1024769. (IF:2.276; JCR分区: Q1.)

[18] Wang LJ#, Gao M, Chen J, Yang ZQ, Sun J, Wang Z, Huang X, Yuan T, Shen X, Xian SX*.Resveratrol Ameliorates Pressure Overload-induced Cardiac Dysfunction and Attenuates Autophagy in Rats. J Cardiovasc Pharmacol. 2015 Oct; 66(4):376-82.( IF:3.105; JCR分区:Q2.)

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